The cysteines of the extracellular loop are crucial for trafficking of human organic cation transporter 2 to the plasma membrane and are involved in oligomerization

Human organic cation transporter 2 (hOCT2) is involved in transport of many endogenous and exogenous organic cations, mainly in kidney and brain cells. Because the quaternary structure of transmembrane proteins plays an essential role for their cellular trafficking and function, we investigated whet...

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Bibliografiska uppgifter
I publikationen:FASEB J
Huvudupphovsmän: Brast, Sabine, Grabner, Alexander, Sucic, Sonja, Sitte, Harald H., Hermann, Edwin, Pavenstädt, Hermann, Schlatter, Eberhard, Ciarimboli, Giuliano
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2011
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4503226/
https://ncbi.nlm.nih.gov/pubmed/22085643
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.11-180679
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