Cisplatin Nephrotoxicity Is Critically Mediated via the Human Organic Cation Transporter 2

Cis-platin is an effective anti-neoplastic agent, but it is also highly nephrotoxic. Here, we clearly identify the human organic cation transporter 2 (hOCT2) as the critical transporter for cis-platin nephrotoxicity in isolated human proximal tubules and offer a potential mechanism for reducing neph...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Ciarimboli, Giuliano, Ludwig, Thomas, Lang, Detlef, Pavenstädt, Hermann, Koepsell, Hermann, Piechota, Hans-Jürgen, Haier, Jörg, Jaehde, Ulrich, Zisowsky, Jochen, Schlatter, Eberhard
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2005
Assuntos:
Original Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1613191/
https://ncbi.nlm.nih.gov/pubmed/16314463
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados