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The Lsm1-7-Pat1 complex promotes viral RNA translation and replication by differential mechanisms

The Lsm1-7-Pat1 complex binds to the 3′ end of cellular mRNAs and promotes 3′ end protection and 5′–3′ decay. Interestingly, this complex also specifically binds to cis-acting regulatory sequences of viral positive-strand RNA genomes promoting their translation and subsequent recruitment from transl...

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Bibliographic Details
Published in:RNA
Main Authors: Jungfleisch, Jennifer, Chowdhury, Ashis, Alves-Rodrigues, Isabel, Tharun, Sundaresan, Díez, Juana
Format: Artigo
Language:Inglês
Published: Cold Spring Harbor Laboratory Press 2015
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4509936/
https://ncbi.nlm.nih.gov/pubmed/26092942
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.052209.115
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