Activation of decapping involves binding of the mRNA and facilitation of the post-binding steps by the Lsm1-7–Pat1 complex

Eitemau Tebyg

• Pat1 contributes to the RNA binding activity of the Lsm1-7–Pat1 complex
  gan: Chowdhury, Ashis, et al.
  Cyhoeddwyd: (2014)
• lsm1 mutations impairing the ability of the Lsm1p-7p-Pat1p complex to preferentially bind to oligoadenylated RNA affect mRNA decay in vivo
  gan: Chowdhury, Ashis, et al.
  Cyhoeddwyd: (2008)
• The decapping activator Lsm1p-7p–Pat1p complex has the intrinsic ability to distinguish between oligoadenylated and polyadenylated RNAs
  gan: Chowdhury, Ashis, et al.
  Cyhoeddwyd: (2007)
• Both Sm-domain and C-terminal extension of Lsm1 are important for the RNA-binding activity of the Lsm1–7–Pat1 complex
  gan: Chowdhury, Ashis, et al.
  Cyhoeddwyd: (2012)
• Mutations in the Saccharomyces cerevisiae LSM1 Gene That Affect mRNA Decapping and 3′ End Protection
  gan: Tharun, Sundaresan, et al.
  Cyhoeddwyd: (2005)