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Mutations in the Saccharomyces cerevisiae LSM1 Gene That Affect mRNA Decapping and 3′ End Protection

The decapping of eukaryotic mRNAs is a key step in their degradation. The heteroheptameric Lsm1p–7p complex is a general activator of decapping and also functions in protecting the 3′ ends of deadenylated mRNAs from a 3′-trimming reaction. Lsm1p is the unique member of the Lsm1p–7p complex, distingu...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Tharun, Sundaresan, Muhlrad, Denise, Chowdhury, Ashis, Parker, Roy
Format: Artigo
Sprache:Inglês
Veröffentlicht: Genetics Society of America 2005
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1449704/
https://ncbi.nlm.nih.gov/pubmed/15716506
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.104.034322
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