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MAGE-RING Protein Complexes Comprise a Family of E3 Ubiquitin Ligases

The melanoma antigen (MAGE) family consists of more than 60 genes, many of which are cancer-testis antigens that are highly expressed in cancer and play a critical role in tumorigenesis. However, the biochemical and cellular functions of this enigmatic family of proteins have remained elusive. Here,...

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發表在:Mol Cell
Main Authors: Doyle, Jennifer M., Gao, Jinlan, Wang, Jiawei, Yang, Maojun, Potts, Patrick Ryan
格式: Artigo
語言:Inglês
出版: 2010
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4509788/
https://ncbi.nlm.nih.gov/pubmed/20864041
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2010.08.029
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