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APC2 Cullin Protein and APC11 RING Protein Comprise the Minimal Ubiquitin Ligase Module of the Anaphase-promoting Complex

In mitosis, the anaphase-promoting complex (APC) regulates the onset of sister-chromatid separation and exit from mitosis by mediating the ubiquitination and degradation of the securin protein and mitotic cyclins. With the use of a baculoviral expression system, we have reconstituted the ubiquitin l...

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Detalhes bibliográficos
Publicado no:Mol Biol Cell
Principais autores: Tang, Zhanyun, Li, Bing, Bharadwaj, Rajnish, Zhu, Haizhen, Özkan, Engin, Hakala, Kevin, Deisenhofer, Johann, Yu, Hongtao
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Cell Biology 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC60759/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11739784/
https://ncbi.nlm.nih.govhttps://doi.org/10.1091/mbc.12.12.3839
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