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Regulation of MAGE‐A3/6 by the CRL4‐DCAF12 ubiquitin ligase and nutrient availability

Melanoma antigen genes (MAGEs) are emerging as important oncogenic drivers that are normally restricted to expression in male germ cells but are aberrantly expressed in cancers and promote tumorigenesis. Mechanistically, MAGEs function as substrate specifying subunits of E3 ubiquitin ligases. Thus,...

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Detalhes bibliográficos
Publicado no:EMBO Rep
Main Authors: Ravichandran, Ramya, Kodali, Kiran, Peng, Junmin, Potts, Patrick Ryan
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6607007/
https://ncbi.nlm.nih.gov/pubmed/31267705
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201847352
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