MAGE-RING Protein Complexes Comprise a Family of E3 Ubiquitin Ligases

The melanoma antigen (MAGE) family consists of more than 60 genes, many of which are cancer-testis antigens that are highly expressed in cancer and play a critical role in tumorigenesis. However, the biochemical and cellular functions of this enigmatic family of proteins have remained elusive. Here,...

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Udgivet i:Mol Cell
Main Authors: Doyle, Jennifer M., Gao, Jinlan, Wang, Jiawei, Yang, Maojun, Potts, Patrick Ryan
Format: Artigo
Sprog:Inglês
Udgivet: 2010
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4509788/
https://ncbi.nlm.nih.gov/pubmed/20864041
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2010.08.029
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