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Reactive Oxygen Species and Mitochondrial DNA Damage and Repair in BCR-ABL1 Cells Resistant to Imatinib

Imatinib revolutionized the therapy of chronic myeloid leukemia (CML), but the resistance to it became an emerging problem. We reported previously that CML cells expressing the BCR/ABL1 fusion gene, accumulated a high level of reactive oxygen species (ROS) due to deregulated mitochondrial electron t...

詳細記述

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書誌詳細
出版年:Biores Open Access
主要な著者: Blasiak, Janusz, Hoser, Grazyna, Bialkowska-Warzecha, Jolanta, Pawlowska, Elzbieta, Skorski, Tomasz
フォーマット: Artigo
言語:Inglês
出版事項: Mary Ann Liebert, Inc. 2015
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4509616/
https://ncbi.nlm.nih.gov/pubmed/26309809
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/biores.2015.0022
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