ALDH2 attenuates Dox-induced cardiotoxicity by inhibiting cardiac apoptosis and oxidative stress

The anthracycline chemotherapy drug doxorubicin (DOX) is cardiotoxic. This study aimed to explore the effect of acetaldehyde dehydrogenase 2 (ALDH2), a detoxifying protein, on DOX-induced cardiotoxicity and unveil the underlying mechanisms. BALB/c mice were randomly divided in four groups: control g...

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Veröffentlicht in:Int J Clin Exp Med
Hauptverfasser: Gao, Yawen, Xu, Yan, Hua, Songwen, Zhou, Shenghua, Wang, Kangkai
Format: Artigo
Sprache:Inglês
Veröffentlicht: e-Century Publishing Corporation 2015
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Original Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4509162/
https://ncbi.nlm.nih.gov/pubmed/26221217
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