Peroxiredoxin-1 Overexpression Attenuates Doxorubicin-Induced Cardiotoxicity by Inhibiting Oxidative Stress and Cardiomyocyte Apoptosis

Background. Previous research has shown that peroxiredoxin 1 (Prdx1) is an important modulator of physiological and pathophysiological cardiovascular events. This study is aimed at investigating the role and underlying mechanism of Prdx1 in doxorubicin- (DOX-) induced cardiotoxicity. Cardiac-specifi...

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Publicat a:Oxid Med Cell Longev
Autors principals: Jiang, Lai, Gong, Yanping, Hu, Yida, You, Yangyang, Wang, Jiawu, Zhang, Zhetao, Wei, Zeyuan, Tang, Chaoliang
Format: Artigo
Idioma:Inglês
Publicat: Hindawi 2020
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7411498/
https://ncbi.nlm.nih.gov/pubmed/32802259
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2020/2405135
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