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Silencing the NR2B gene in rat ACC neurons by lentivirus-delivered shRNA alleviates pain-related aversion

The N-methyl-D-aspartate (NMDA) receptor NR2B subunit on neurons in the anterior cingulate cortex (ACC) is implicated in the affective response to noxious stimuli. Selectively silencing this NR2B subunit in ACC neurons could therefore alleviate pain-related aversion. However, to date, there is no op...

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Detalhes bibliográficos
Publicado no:Int J Clin Exp Med
Main Authors: Guo, Shou-Gang, Lv, Xiu-Hua, Guan, Shan-Hui, Li, Hui-Lu, Qiao, Yong, Feng, Hao, Cong, Lin, Wang, Gong-Ming
Formato: Artigo
Idioma:Inglês
Publicado em: e-Century Publishing Corporation 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4509155/
https://ncbi.nlm.nih.gov/pubmed/26221210
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