Silencing the NR2B gene in rat ACC neurons by lentivirus-delivered shRNA alleviates pain-related aversion

The N-methyl-D-aspartate (NMDA) receptor NR2B subunit on neurons in the anterior cingulate cortex (ACC) is implicated in the affective response to noxious stimuli. Selectively silencing this NR2B subunit in ACC neurons could therefore alleviate pain-related aversion. However, to date, there is no op...

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Vydáno v:Int J Clin Exp Med
Hlavní autoři: Guo, Shou-Gang, Lv, Xiu-Hua, Guan, Shan-Hui, Li, Hui-Lu, Qiao, Yong, Feng, Hao, Cong, Lin, Wang, Gong-Ming
Médium: Artigo
Jazyk:Inglês
Vydáno: e-Century Publishing Corporation 2015
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Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4509155/
https://ncbi.nlm.nih.gov/pubmed/26221210
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