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Homocysteine Induces Collagen I Expression by Downregulating Histone Methyltransferase G9a

Hyperhomocysteinemia (HHcy) leads to several clinical manifestations including hepatic fibrosis. Excess deposition of extracellular matrix (ECM) components including collagen is the eponymous lesion of liver fibrosis. In this study, we demonstrated that elevated concentration of Hcy induced the expr...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Lei, Wenjing, Long, Yanjun, Li, Shuang, Liu, Ze, Zhu, Fengxin, Hou, Fan Fan, Nie, Jing
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4508059/
https://ncbi.nlm.nih.gov/pubmed/26192994
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0130421
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