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Homocysteine Induces Collagen I Expression by Downregulating Histone Methyltransferase G9a

Hyperhomocysteinemia (HHcy) leads to several clinical manifestations including hepatic fibrosis. Excess deposition of extracellular matrix (ECM) components including collagen is the eponymous lesion of liver fibrosis. In this study, we demonstrated that elevated concentration of Hcy induced the expr...

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Bibliografiske detaljer
Udgivet i:PLoS One
Main Authors: Lei, Wenjing, Long, Yanjun, Li, Shuang, Liu, Ze, Zhu, Fengxin, Hou, Fan Fan, Nie, Jing
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4508059/
https://ncbi.nlm.nih.gov/pubmed/26192994
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0130421
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