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Homocysteine Induces Collagen I Expression by Downregulating Histone Methyltransferase G9a

Hyperhomocysteinemia (HHcy) leads to several clinical manifestations including hepatic fibrosis. Excess deposition of extracellular matrix (ECM) components including collagen is the eponymous lesion of liver fibrosis. In this study, we demonstrated that elevated concentration of Hcy induced the expr...

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Podrobná bibliografie
Vydáno v:PLoS One
Hlavní autoři: Lei, Wenjing, Long, Yanjun, Li, Shuang, Liu, Ze, Zhu, Fengxin, Hou, Fan Fan, Nie, Jing
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4508059/
https://ncbi.nlm.nih.gov/pubmed/26192994
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0130421
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