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Batf3 maintains Irf8 autoactivation for commitment of a CD8α(+) cDC clonogenic progenitor
The transcription factors Batf3 and IRF8 are required for development of CD8α(+) conventional dendritic cells (cDCs), but the basis for their actions was unclear. Here, we identify two novel Zbtb46(+) progenitors that separately generate CD8α(+) and CD4(+) cDCs and arise directly from the common DC...
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| Veröffentlicht in: | Nat Immunol |
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| Hauptverfasser: | , , , , , , , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2015
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4507574/ https://ncbi.nlm.nih.gov/pubmed/26054719 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni.3197 |
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