Distinct transcriptional programs control cross-priming in classical- and monocyte-derived dendritic cells

Both classical DCs (cDCs) and monocyte-derived DCs (Mo-DCs) are capable of cross-priming CD8(+) T cells in response to cell-associated antigens. We found that Ly-6C(hi)TREML4(−) monocytes can differentiate into Zbtb46(+) Mo-DCs in response to GM-CSF and IL-4, but that Ly-6C(hi)TREML4(+) monocytes we...

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Publicado en:Cell Rep
Autores principales: Briseño, Carlos G., Haldar, Malay, Kretzer, Nicole M., Wu, Xiaodi, Theisen, Derek J., Wumesh, KC, Durai, Vivek, Grajales-Reyes, Gary E., Iwata, Arifumi, Bagadia, Prachi, Murphy, Theresa L., Murphy, Kenneth M.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2016
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4941620/
https://ncbi.nlm.nih.gov/pubmed/27264183
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2016.05.025
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