Development and validation of an UPLC-MS/MS method for the quantification of ethoxzolamide in plasma and bioequivalent buffers: Applications to absorption, brain distribution, and pharmacokinetic studies

The purpose of this study is to develop and validate an UPLC-MS/MS method to quantify ethoxzolamide in plasma (EZ) and apply the method to absorption, brain distribution, as well as pharmacokinetic studies. A C(18) column was used with 0.1% of formic acid in acetonitrile and 0.1% of formic acid in w...

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Detalhes bibliográficos
Publicado no:J Chromatogr B Analyt Technol Biomed Life Sci
Main Authors: Gao, Song, Zhao, Jing, Yin, Taijun, Ma, Yong, Xu, Beibei, Moore, Anthony N., Dash, Pramod K., Hu, Ming
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4507571/
https://ncbi.nlm.nih.gov/pubmed/25706567
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jchromb.2015.01.034
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