Effect of bipolar androgen therapy for asymptomatic men with castration-resistant prostate cancer: Results from a pilot clinical study

Targeting androgen receptor (AR) axis signaling by disrupting androgen-AR interactions remains the primary treatment for metastatic prostate cancer. Unfortunately, all men develop resistance to primary castrating therapy and secondary androgen deprivation therapies (ADTs). Resistance develops in par...

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Dades bibliogràfiques
Publicat a:Sci Transl Med
Autors principals: Schweizer, Michael T., Antonarakis, Emmanuel S., Wang, Hao, Ajiboye, A. Seun, Spitz, Avery, Cao, Haiyi, Luo, Jun, Haffner, Michael C., Yegnasubramanian, Srinivasan, Carducci, Michael A., Eisenberger, Mario A., Isaacs, John T., Denmeade, Samuel R.
Format: Artigo
Idioma:Inglês
Publicat: 2015
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4507510/
https://ncbi.nlm.nih.gov/pubmed/25568070
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.3010563
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