Effect of bipolar androgen therapy for asymptomatic men with castration-resistant prostate cancer: Results from a pilot clinical study

Targeting androgen receptor (AR) axis signaling by disrupting androgen-AR interactions remains the primary treatment for metastatic prostate cancer. Unfortunately, all men develop resistance to primary castrating therapy and secondary androgen deprivation therapies (ADTs). Resistance develops in par...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Sci Transl Med
Main Authors: Schweizer, Michael T., Antonarakis, Emmanuel S., Wang, Hao, Ajiboye, A. Seun, Spitz, Avery, Cao, Haiyi, Luo, Jun, Haffner, Michael C., Yegnasubramanian, Srinivasan, Carducci, Michael A., Eisenberger, Mario A., Isaacs, John T., Denmeade, Samuel R.
Format: Artigo
Jezik:Inglês
Izdano: 2015
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4507510/
https://ncbi.nlm.nih.gov/pubmed/25568070
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.3010563
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