Effect of bipolar androgen therapy for asymptomatic men with castration-resistant prostate cancer: Results from a pilot clinical study

Targeting androgen receptor (AR) axis signaling by disrupting androgen-AR interactions remains the primary treatment for metastatic prostate cancer. Unfortunately, all men develop resistance to primary castrating therapy and secondary androgen deprivation therapies (ADTs). Resistance develops in par...

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Publicado en:Sci Transl Med
Autores principales: Schweizer, Michael T., Antonarakis, Emmanuel S., Wang, Hao, Ajiboye, A. Seun, Spitz, Avery, Cao, Haiyi, Luo, Jun, Haffner, Michael C., Yegnasubramanian, Srinivasan, Carducci, Michael A., Eisenberger, Mario A., Isaacs, John T., Denmeade, Samuel R.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2015
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4507510/
https://ncbi.nlm.nih.gov/pubmed/25568070
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.3010563
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