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Luciferin Amides Enable in Vivo Bioluminescence Detection of Endogenous Fatty Acid Amide Hydrolase Activity
[Image: see text] Firefly luciferase is homologous to fatty acyl-CoA synthetases. We hypothesized that the firefly luciferase substrate d-luciferin and its analogs are fatty acid mimics that are ideally suited to probe the chemistry of enzymes that release fatty acid products. Here, we synthesized l...
Gardado en:
| Publicado en: | J Am Chem Soc |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
American Chemical
Society
2015
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| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4507478/ https://ncbi.nlm.nih.gov/pubmed/26120870 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.5b04357 |
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