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Beyond D-luciferin: Expanding the Scope of Bioluminescence Imaging in vivo

The light-emitting chemical reaction catalyzed by the enzyme firefly luciferase is widely used for noninvasive imaging in live mice. However, photon emission from the luciferase is critically dependent on the chemical properties of its substrate, D-luciferin. In this review, we describe recent work...

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Bibliografiske detaljer
Main Authors: Adams, Spencer T., Miller, Stephen C.
Format: Artigo
Sprog:Inglês
Udgivet: 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4149945/
https://ncbi.nlm.nih.gov/pubmed/25078002
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cbpa.2014.07.003
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