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The Drug Excipient Cyclodextrin Interacts With d-Luciferin and Interferes With Bioluminescence Imaging

Cyclodextrins are well-characterized, barrel-shaped molecules that can solubilize organic small molecules in aqueous solution via host–guest interactions. As such, cyclodextrins are used as excipients for experimental therapeutics in vivo. We observed unanticipated modifications to bioluminescence i...

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Detalhes bibliográficos
Publicado no:Mol Imaging
Main Authors: Kumar, Jeyan S., Miller Jenkins, Lisa M., Gottesman, Michael M., Hall, Matthew D.
Formato: Artigo
Idioma:Inglês
Publicado em: SAGE Publications 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4982550/
https://ncbi.nlm.nih.gov/pubmed/27030398
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1536012115625225
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