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Beyond D-luciferin: Expanding the Scope of Bioluminescence Imaging in vivo

The light-emitting chemical reaction catalyzed by the enzyme firefly luciferase is widely used for noninvasive imaging in live mice. However, photon emission from the luciferase is critically dependent on the chemical properties of its substrate, D-luciferin. In this review, we describe recent work...

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Detalles Bibliográficos
Main Authors: Adams, Spencer T., Miller, Stephen C.
Formato: Artigo
Idioma:Inglês
Publicado: 2014
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4149945/
https://ncbi.nlm.nih.gov/pubmed/25078002
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cbpa.2014.07.003
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