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Overexpression of Bovine FcRn in Mice Enhances T-Dependent Immune Responses by Amplifying T Helper Cell Frequency and Germinal Center Enlargement in the Spleen

The neonatal Fc receptor (FcRn) plays key roles in IgG and albumin homeostasis, maternal IgG transport, and antigen presentation of IgG-opsonized antigens. Previously, we reported that transgenic (Tg) mice that overexpress the bovine FcRn (bFcRn) have augmented T-dependent humoral immune response wi...

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Detaylı Bibliyografya
Yayımlandı:Front Immunol
Asıl Yazarlar: Schneider, Zita, Jani, Péter Károly, Szikora, Bence, Végh, Attila, Kövesdi, Dorottya, Iliás, Attila, Cervenak, Judit, Balogh, Péter, Kurucz, István, Kacskovics, Imre
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Frontiers Media S.A. 2015
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4507463/
https://ncbi.nlm.nih.gov/pubmed/26257730
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2015.00357
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