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FcRn overexpression in mice results in potent humoral response against weakly immunogenic antigen
The neonatal Fc receptor (FcRn) regulates IgG and albumin homeostasis, mediates maternal IgG transport, is active in phagocytosis and delivers antigen for presentation. We have previously shown that transgenic (tg) mice that have been created to overexpress bovine FcRn (bFcRn) demonstrate increased...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Landes Bioscience
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3092618/ https://ncbi.nlm.nih.gov/pubmed/21239891 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/mabs.3.2.14462 |
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