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FcRn overexpression in mice results in potent humoral response against weakly immunogenic antigen
The neonatal Fc receptor (FcRn) regulates IgG and albumin homeostasis, mediates maternal IgG transport, is active in phagocytosis and delivers antigen for presentation. We have previously shown that transgenic (tg) mice that have been created to overexpress bovine FcRn (bFcRn) demonstrate increased...
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| Autores principales: | , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Landes Bioscience
2011
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3092618/ https://ncbi.nlm.nih.gov/pubmed/21239891 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/mabs.3.2.14462 |
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