DNA Triplex-Based Complexes Display Anti-HIV-1-Cell Fusion Activity

DNA triplexes with hydrophobic modifications were designed and evaluated for their activity as inhibitors of the cell fusion of human immunodeficiency virus type 1 (HIV-1). Triplex inhibitors displayed low micromolar activities in the cell–cell fusion assay and nanomolar activities in the anti-HIV-1...

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Detalhes bibliográficos
Publicado no:Nucleic Acid Ther
Main Authors: Xu, Liang, Zhang, Tao, Xu, Xiaoyu, Chong, Huihui, Lai, Wenqing, Jiang, Xifeng, Wang, Chao, He, Yuxian, Liu, Keliang
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2015
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4507350/
https://ncbi.nlm.nih.gov/pubmed/26192705
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/nat.2015.0535
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