DNA Duplexes with Hydrophobic Modifications Inhibit Fusion between HIV-1 and Cell Membranes

Discovery of new drugs for the treatment of AIDS typically possessing unique structures associated with novel mechanisms of action has been of great importance due to the quick drug-resistant mutations of HIV-1 strains. The work presented in this report describes a novel class of DNA duplex-based HI...

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Bibliographische Detailangaben
Hauptverfasser: Xu, Liang, Cai, Lifeng, Chen, Xueliang, Jiang, Xifeng, Chong, Huihui, Zheng, Baohua, Wang, Kun, He, Junlin, Chen, Wei, Zhang, Tao, Cheng, Maosheng, He, Yuxian, Liu, Keliang
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2013
Schlagworte:
Antiviral Agents
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3811431/
https://ncbi.nlm.nih.gov/pubmed/23896466
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00758-13
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