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Structural Basis of Potent and Broad HIV-1 Fusion Inhibitor CP32M
CP32M is a newly designed peptide fusion inhibitor possessing potent anti-HIV activity, especially against T20-resistant HIV-1 strains. In this study, we show that CP32M can efficiently inhibit a large panel of diverse HIV-1 variants, including subtype B′, CRF07_BC, and CRF01_AE recombinants and nat...
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| Главные авторы: | , , , , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
American Society for Biochemistry and Molecular Biology
2012
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3411002/ https://ncbi.nlm.nih.gov/pubmed/22679024 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.381079 |
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