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PDGFRβ signaling regulates local inflammation and synergizes with hypercholesterolemia to promote atherosclerosis
Platelet-derived growth factor (PDGF) is a mitogen and chemoattractant for vascular smooth muscle cells (VSMCs). However, the direct effects of PDGF receptor β (PDGFRβ) activation on VSMCs have not been studied in the context of atherosclerosis. Here, we present a new mouse model of atherosclerosis...
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| Publicado en: | Nat Commun |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2015
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4507293/ https://ncbi.nlm.nih.gov/pubmed/26183159 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms8770 |
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