Dysregulated mesenchymal PDGFR‐β drives kidney fibrosis

Kidney fibrosis is characterized by expansion and activation of platelet‐derived growth factor receptor‐β (PDGFR‐β)‐positive mesenchymal cells. To study the consequences of PDGFR‐β activation, we developed a model of primary renal fibrosis using transgenic mice with PDGFR‐β activation specifically i...

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Publicado no:EMBO Mol Med
Main Authors: Buhl, Eva M, Djudjaj, Sonja, Klinkhammer, Barbara M, Ermert, Katja, Puelles, Victor G, Lindenmeyer, Maja T, Cohen, Clemens D, He, Chaoyong, Borkham‐Kamphorst, Erawan, Weiskirchen, Ralf, Denecke, Bernd, Trairatphisan, Panuwat, Saez‐Rodriguez, Julio, Huber, Tobias B, Olson, Lorin E, Floege, Jürgen, Boor, Peter
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7059015/
https://ncbi.nlm.nih.gov/pubmed/31943786
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/emmm.201911021
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