Dysregulated mesenchymal PDGFR‐β drives kidney fibrosis

Kidney fibrosis is characterized by expansion and activation of platelet‐derived growth factor receptor‐β (PDGFR‐β)‐positive mesenchymal cells. To study the consequences of PDGFR‐β activation, we developed a model of primary renal fibrosis using transgenic mice with PDGFR‐β activation specifically i...

Descripción completa

Guardado en:
Detalles Bibliográficos
Publicado en:EMBO Mol Med
Autores principales: Buhl, Eva M, Djudjaj, Sonja, Klinkhammer, Barbara M, Ermert, Katja, Puelles, Victor G, Lindenmeyer, Maja T, Cohen, Clemens D, He, Chaoyong, Borkham‐Kamphorst, Erawan, Weiskirchen, Ralf, Denecke, Bernd, Trairatphisan, Panuwat, Saez‐Rodriguez, Julio, Huber, Tobias B, Olson, Lorin E, Floege, Jürgen, Boor, Peter
Formato: Artigo
Lenguaje:Inglês
Publicado: John Wiley and Sons Inc. 2020
Materias:
Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7059015/
https://ncbi.nlm.nih.gov/pubmed/31943786
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/emmm.201911021
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares