STAT1 modulates tissue wasting or overgrowth downstream from PDGFRβ

Platelet-derived growth factor (PDGF) acts through two conserved receptor tyrosine kinases: PDGFRα and PDGFRβ. Gain-of-function mutations in human PDGFRB have been linked recently to genetic diseases characterized by connective tissue wasting (Penttinen syndrome) or overgrowth (Kosaki overgrowth syn...

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Bibliografische gegevens
Gepubliceerd in:Genes Dev
Hoofdauteurs: He, Chaoyong, Medley, Shayna C., Kim, Jang, Sun, Chengyi, Kwon, Hae Ryong, Sakashita, Hiromi, Pincu, Yair, Yao, Longbiao, Eppard, Danielle, Dai, Bojie, Berry, William L., Griffin, Timothy M., Olson, Lorin E.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Cold Spring Harbor Laboratory Press 2017
Onderwerpen:
Research Paper
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5647937/
https://ncbi.nlm.nih.gov/pubmed/28924035
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.300384.117
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