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Directed Evolution of RebH for Site Selective Halogenation of Large, Biologically Active Molecules()
We recently characterized the substrate scope of wild-type RebH and evolved variants of this enzyme with improved stability for biocatalysis. The substrate scopes of both RebH and the stabilized variants, however, are limited primarily to compounds similar in size to tryptophan. We have now used a s...
में बचाया:
| में प्रकाशित: | Angew Chem Int Ed Engl |
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| मुख्य लेखकों: | , , |
| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
2015
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4506780/ https://ncbi.nlm.nih.gov/pubmed/25678465 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201411901 |
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