α-enolase Causes Pro-Inflammatory Activation of Pulmonary Microvascular Endothelial Cells and Primes Neutrophils through Plasmin Activation of Protease-Activated Receptor-2

Pro-inflammatory activation of vascular endothelium leading to increased surface expression of adhesion molecules and neutrophil (PMN) sequestration and subsequent activation is paramount in the development of acute lung (ALI) and organ injury in injured patients. We hypothesize that α-enolase, whic...

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Publicado no:Shock
Main Authors: Bock, Ashley, Tucker, Nicole, Kelher, Marguerite R., Khan, Samina Y., Gonzalez, Eduardo, Wohlauer, Max, Hansen, Kirk, Dzieciatkowska, Monika, Sauaia, Angels, Banerjee, Anirban, Moore, Ernest E., Silliman, Christopher C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4506257/
https://ncbi.nlm.nih.gov/pubmed/25944790
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/SHK.0000000000000394
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