Antibodies to major histocompatibility complex class II antigens directly prime neutrophils and cause acute lung injury in a two-event in vivo rat model

BACKGROUND: Transfusion-related acute lung injury (TRALI) is a significant cause of mortality, especially after transfusions containing antibodies to major histocompatibility complex (MHC) class II antigens. We hypothesize that a first event induces both 1) polymorphonuclear neutrophils (PMNs) to ex...

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Detalhes bibliográficos
Publicado no:Transfusion
Main Authors: Kelher, Marguerite R., Banerjee, Anirban, Gamboni, Fabia, Anderson, Cameron, Silliman, Christopher C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5787352/
https://ncbi.nlm.nih.gov/pubmed/27667662
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/trf.13817
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