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Hypertonic Saline Inhibits Arachidonic Acid Priming of the Human Neutrophil Oxidase

BACKGROUND: Arachidonic acid (AA, and its leukotriene derivatives e.g.: LTB(4)) is an inflammatory mediator in post-shock mesenteric lymph that appears to act as an agonist on G-protein coupled receptors (GPCRs). These mediators prime neutrophils (PMNs) for an increased production of superoxide, imp...

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Auteurs principaux: Lee, Luis, Kelher, Marguerite R., Moore, Ernest E., Banerjee, Anirban, Silliman, Christopher C.
Format: Artigo
Langue:Inglês
Publié: 2011
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3229642/
https://ncbi.nlm.nih.gov/pubmed/21816415
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jss.2011.06.022
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