Wordt geladen...

Conversion of abiraterone to D4A drives antitumor activity in prostate cancer

Prostate cancer resistance to castration occurs because tumors acquire the metabolic capability of converting precursor steroids to 5α-dihydrotestosterone (DHT), promoting signaling by the androgen receptor (AR) and the development of castration-resistant prostate cancer (CRPC)(1–3). Essential for r...

Volledige beschrijving

Bewaard in:
Bibliografische gegevens
Gepubliceerd in:Nature
Hoofdauteurs: Li, Zhenfei, Bishop, Andrew, Alyamani, Mohammad, Garcia, Jorge A., Dreicer, Robert, Bunch, Dustin, Liu, Jiayan, Upadhyay, Sunil K., Auchus, Richard J., Sharifi, Nima
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2015
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4506215/
https://ncbi.nlm.nih.gov/pubmed/26030522
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature14406
Tags: Voeg label toe
Geen labels, Wees de eerste die dit record labelt!