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Vimentin Phosphorylation Underlies Myofibroblast Sensitivity to Withaferin A In Vitro and during Corneal Fibrosis

Vimentin is a newly recognized target for corneal fibrosis. Using primary rabbit corneal fibroblasts and myofibroblasts we show that myofibroblasts, unlike fibroblasts, display impaired cell spreading and cell polarization, which is associated with increased levels of soluble serine-38 phosphorylate...

詳細記述

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書誌詳細
出版年:PLoS One
主要な著者: Bargagna-Mohan, Paola, Lei, Ling, Thompson, Alexis, Shaw, Camille, Kasahara, Kousuke, Inagaki, Masaki, Mohan, Royce
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science 2015
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4506086/
https://ncbi.nlm.nih.gov/pubmed/26186445
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0133399
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