Withaferin A Targets Intermediate Filaments Glial Fibrillary Acidic Protein and Vimentin in a Model of Retinal Gliosis

Gliosis is a biological process that occurs during injury repair in the central nervous system and is characterized by the overexpression of the intermediate filaments (IFs) glial fibrillary acidic protein (GFAP) and vimentin. A common thread in many retinal diseases is reactive Müller cell gliosis,...

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Detalles Bibliográficos
Autores principales: Bargagna-Mohan, Paola, Paranthan, Riya R., Hamza, Adel, Dimova, Neviana, Trucchi, Beatrice, Srinivasan, Cidambi, Elliott, Gregory I., Zhan, Chang-Guo, Lau, Daniel L., Zhu, Haiyan, Kasahara, Kousuke, Inagaki, Masaki, Cambi, Franca, Mohan, Royce
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2010
Materias:
Protein Synthesis and Degradation
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2844212/
https://ncbi.nlm.nih.gov/pubmed/20048155
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.093765
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