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Nrl-Knockout Mice Deficient in Rpe65 Fail to Synthesize 11-cis Retinal and Cone Outer Segments
PURPOSE: To define rod and cone function further in terms of visual cycle mechanism, the retinal phenotype resulting from Rpe65 (retinoid isomerase I) deficiency in Nrl(−/−) mice having a single class of photoreceptors resembling wild-type cones was characterized and outcomes of retinoid supplementa...
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| Publicat a: | Invest Ophthalmol Vis Sci |
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| Autors principals: | , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2008
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4505835/ https://ncbi.nlm.nih.gov/pubmed/18326740 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.07-1234 |
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