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Examining the Role of Cone-expressed RPE65 in Mouse Cone Function

Efficient chromophore supply is paramount for the continuous function of vertebrate cone photoreceptors. It is well established that isomerization of all-trans- to 11-cis- retinoid in the retinal pigmented epithelium by RPE65 is a key reaction in this process. Mutations in RPE65 result in a disrupte...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Kolesnikov, Alexander V., Tang, Peter H., Kefalov, Vladimir J.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6155087/
https://ncbi.nlm.nih.gov/pubmed/30242264
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-32667-w
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