Human cone photoreceptor dependence on RPE65 isomerase

The visual (retinoid) cycle, the enzymatic pathway that regenerates chromophore after light absorption, is located primarily in the retinal pigment epithelium (RPE) and is essential for rod photoreceptor survival. Whether this pathway also is essential for cone photoreceptor survival is unknown, and...

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Main Authors: Jacobson, Samuel G., Aleman, Tomas S., Cideciyan, Artur V., Heon, Elise, Golczak, Marcin, Beltran, William A., Sumaroka, Alexander, Schwartz, Sharon B., Roman, Alejandro J., Windsor, Elizabeth A. M., Wilson, James M., Aguirre, Gustavo D., Stone, Edwin M., Palczewski, Krzysztof
Formáid: Artigo
Teanga:Inglês
Foilsithe: National Academy of Sciences 2007
Ábhair:
Biological Sciences
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1986623/
https://ncbi.nlm.nih.gov/pubmed/17848510
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0706367104
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