Human cone photoreceptor dependence on RPE65 isomerase

The visual (retinoid) cycle, the enzymatic pathway that regenerates chromophore after light absorption, is located primarily in the retinal pigment epithelium (RPE) and is essential for rod photoreceptor survival. Whether this pathway also is essential for cone photoreceptor survival is unknown, and...

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Bibliografiske detaljer
Main Authors: Jacobson, Samuel G., Aleman, Tomas S., Cideciyan, Artur V., Heon, Elise, Golczak, Marcin, Beltran, William A., Sumaroka, Alexander, Schwartz, Sharon B., Roman, Alejandro J., Windsor, Elizabeth A. M., Wilson, James M., Aguirre, Gustavo D., Stone, Edwin M., Palczewski, Krzysztof
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2007
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1986623/
https://ncbi.nlm.nih.gov/pubmed/17848510
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0706367104
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