Human cone photoreceptor dependence on RPE65 isomerase

The visual (retinoid) cycle, the enzymatic pathway that regenerates chromophore after light absorption, is located primarily in the retinal pigment epithelium (RPE) and is essential for rod photoreceptor survival. Whether this pathway also is essential for cone photoreceptor survival is unknown, and...

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Detalhes bibliográficos
Main Authors: Jacobson, Samuel G., Aleman, Tomas S., Cideciyan, Artur V., Heon, Elise, Golczak, Marcin, Beltran, William A., Sumaroka, Alexander, Schwartz, Sharon B., Roman, Alejandro J., Windsor, Elizabeth A. M., Wilson, James M., Aguirre, Gustavo D., Stone, Edwin M., Palczewski, Krzysztof
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2007
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1986623/
https://ncbi.nlm.nih.gov/pubmed/17848510
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0706367104
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