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Nrl-Knockout Mice Deficient in Rpe65 Fail to Synthesize 11-cis Retinal and Cone Outer Segments
PURPOSE: To define rod and cone function further in terms of visual cycle mechanism, the retinal phenotype resulting from Rpe65 (retinoid isomerase I) deficiency in Nrl(−/−) mice having a single class of photoreceptors resembling wild-type cones was characterized and outcomes of retinoid supplementa...
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| Veröffentlicht in: | Invest Ophthalmol Vis Sci |
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| Hauptverfasser: | , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2008
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4505835/ https://ncbi.nlm.nih.gov/pubmed/18326740 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.07-1234 |
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