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A signaling-induced switch in Dicer localization and function

In this issue of Developmental Cell, Drake and colleagues (2014) report that Ras signaling results in Dicer phosphorylation, which induces its nuclear localization and modulates its function. This regulatory strategy, conserved in mammals, allows dynamic control of miRNA function required for C. ele...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Dev Cell
Prif Awduron: Hu, Fuqu, Lai, Eric C., Okamura, Katsutomo
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2014
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4505742/
https://ncbi.nlm.nih.gov/pubmed/25490263
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2014.11.032
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