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A signaling-induced switch in Dicer localization and function
In this issue of Developmental Cell, Drake and colleagues (2014) report that Ras signaling results in Dicer phosphorylation, which induces its nuclear localization and modulates its function. This regulatory strategy, conserved in mammals, allows dynamic control of miRNA function required for C. ele...
Shranjeno v:
| izdano v: | Dev Cell |
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| Main Authors: | , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2014
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4505742/ https://ncbi.nlm.nih.gov/pubmed/25490263 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2014.11.032 |
| Oznake: |
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