Thiobenzothiazole-modified Hydrocortisones Display Anti-inflammatory Activity with Reduced Impact on Islet β-Cell Function

Glucocorticoids signal through the glucocorticoid receptor (GR) and are administered clinically for a variety of situations, including inflammatory disorders, specific cancers, rheumatoid arthritis, and organ/tissue transplantation. However, glucocorticoid therapy is also associated with additional...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Burke, Susan J., May, Amanda L., Noland, Robert C., Lu, Danhong, Brissova, Marcela, Powers, Alvin C., Sherrill, Elizabeth M., Karlstad, Michael D., Campagna, Shawn R., Stephens, Jacqueline M., Collier, J. Jason
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2015
Assuntos:
Molecular Bases of Disease
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4505588/
https://ncbi.nlm.nih.gov/pubmed/25851902
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.632190
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