Thiobenzothiazole-modified Hydrocortisones Display Anti-inflammatory Activity with Reduced Impact on Islet β-Cell Function

Glucocorticoids signal through the glucocorticoid receptor (GR) and are administered clinically for a variety of situations, including inflammatory disorders, specific cancers, rheumatoid arthritis, and organ/tissue transplantation. However, glucocorticoid therapy is also associated with additional...

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Dades bibliogràfiques
Publicat a:J Biol Chem
Autors principals: Burke, Susan J., May, Amanda L., Noland, Robert C., Lu, Danhong, Brissova, Marcela, Powers, Alvin C., Sherrill, Elizabeth M., Karlstad, Michael D., Campagna, Shawn R., Stephens, Jacqueline M., Collier, J. Jason
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2015
Matèries:
Molecular Bases of Disease
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4505588/
https://ncbi.nlm.nih.gov/pubmed/25851902
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.632190
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